TY - JOUR ID - 161 TI - Study of Demographic Characteristics of Adult Patients with Positive Urine Culture in a General Hospital in Tehran, Iran JO - Journal of Basic and Clinical Pathophysiology JA - JBCP LA - en SN - 2322-1895 AU - Sahebnasagh, Roxana AU - Saderi, Horieh AU - Safkhani, Elaheh AU - Boroumandi, Shahram AU - Afshar, Reza AD - Molecular Microbiology Research Center, Shahed University, Tehran, Iran AD - School of Medicine, Shahed University, Tehran, Iran AD - Microbiology Laboratory, Pars General Hospital, Tehran, Iran Y1 - 2015 PY - 2015 VL - 3 IS - 1 SP - 7 EP - 12 KW - Bacteria KW - Patients KW - urine culture KW - Antibiotic resistance DO - 10.22070/jbcp.2015.161 N2 - BACKGROUND & OBJECTIVE: Urinary tract infection (UTI) is a common disease in adults that early diagnosis and proper treatment of it has high importance. This study was performed for analysis of type and antibiotics resistance of isolated bacteria from urine of adult in different sex and ages for help in choose of antibiotics in empirical therapy.METHOD: Data of patients (gender, age, kind of admission and isolated bacteria) with bacterial positive urine culture during three months in 2013 at Pars Hospital, Tehran, Iran, were studied and analyzed by SPSS software. Antimicrobial susceptibility pattern of isolates to cotrimoxazole, ampicillin, ciprofloxacin, gentamicin, amikacin and nitrofurantoin, were also determined by the standard disk diffusion method according to CLSI recommendation.RESULTS: A total of 1123 urine isolates were collected. Studied patients were often female and outpatients (78.3% and 88.7%, respectively). Escherichia coli was the most common isolate (50%), followed by Streptococcus agalactiae (22.9%), Klebsiella spp. (8.5%), Enterococcus spp. (7.6%), Coagulase Negative Staphylococci (3.7%) and Staphylococcus aureus (2%). Statistically significant differences were seen in distribution of some bacteria regarding demographic characteristics of patients. Highest resistance rates have shown to cotrimoxazole and ampicillin (56.9% and 55%, respectively) among isolated bacteria.CONCLUSIONS: The results show the relationship between demographic characteristics of Iranian patients and type of isolated bacteria from urine and high resistance to common antimicrobial agents. UR - https://jbcp.shahed.ac.ir/article_161.html L1 - https://jbcp.shahed.ac.ir/article_161_a0d1db662731a4d601455abdd73d6a84.pdf ER -