Journal of Basic and Clinical Pathophysiology

Journal of Basic and Clinical Pathophysiology

Antibacterial effects of methanolic and aqueous extracts of eight plants in traditional medicine

Document Type : Research Paper

Authors
Akbar Sheykhani
Mohammad Niakan
Zahra Mottaghian
Zahra Salahi
Department of Microbiology, Medicine Faculty, Shahed University, Tehran, Iran
10.22070/jbcp.2019.4535.1117
Abstract
Background and Objective: Escherichia coli bacteria often causes infections in the gastrointestinal tract and other parts such as the urinary tract. Staphylococcus aureus is a common pathogen that causes infections in the skin, upper respiratory tract, and many parts of the body. In recent years, resistance to these bacteria has become one of the medical problems of antibiotics. Flowering herbs from the past are used to treat genital and gastrointestinal tract infections, and traditional herbal remedies are used to treat prostatic inflammation, gastric and intestinal ulcers, and lungs, kidneys and bladder problems. Hypericum perforatum is used to relieve the cough, symptoms of common cold, sputum, and healing wounds and injuries. Artemisia absinthium is beneficial for the treatment of arthritis, and inflammation of the spleen and hepatitis and the lavender plant is antiseptic. The aim of this study was to determine the antimicrobial effect of the extracts of these plants.
Materials and Methods: In this study, the antimicrobial effects of aqueous and ethanolic extracts of the above-mentioned plants on standard bacteria were studied. Methanolic and aqueous extracts were performed using standard methods. Serial dilution of the extracts was prepared. The extracts were then concentrated in water bath. Determination of hypersensitivity was done by disc diffusion method for each extract and the findings were analyzed.
Results: The results of this study showed that the alcoholic and aqueous extracts of Artemisia absinthium on Escherichia coli and Achilles millefolium aqueous extract on Staphylococcus aureus have the highest effect. The antimicrobial effect of the aqueous extract of Ruta graveolens and alcoholic extract of Artemisia absinthium was more than the others.
Conclusion: The widespread use of antibiotics and drug resistance has led to more attention to medicinal plants. Some plants extracts have a significant antimicrobial effect. The plants studied in this study had an inhibitory effect on Escherichia coli and Staphylococcus aureus strains. It can be hoped that with further investigation of the various forms of the extracts, effective and safe drugs were obtained to control the bacteria.
Keywords
Escherichia coli
Staphylococcus aureus
Medicinal plants extracts
Antibacterial effects
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