Correlation between lower and higher order sensory functions and manual dexterity in dominant and non-dominant hand of patients with idiopathic Parkinson's disease

Document Type : Research Paper

Authors

1 Master of Science Student Occupational Therapy, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences (IUMS), Tehran, Iran.

2 Assistant Professor in Occupational Therapy Department, School of Rehabilitation sciences, Iran University of Medical Sciences (IUMS), Tehran, Iran.

3 . Master of Science Student Occupational Therapy, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences (IUMS), Tehran, Iran.

4 Student of PhD neuroscience, Master of Occupational Therapy, Department of Advance Technology of Medicine, Iran University of Medical Sciences, Tehran, Iran

5 Lecturer, Department of Occupational Therapy, School of Rehabilitation, Iran University of Medical Sciences (IUMS), Tehran, Iran

Abstract

Objective: To investigate the correlation between lower and higher order sensory functions and manual dexterity as well as to identify the sensory measures that could predict manual dexterity in patients with idiopathic Parkinson’s disease (PD).
Materials and methods: In this cross-sectional study, 55 patients with idiopathic PD by mean age of 59.85 ± 11.89 years, and mean Hoehn and Yahr stage of 2.76 ± 1.37 were non-randomly selected. Lower order sensory function (i.e., light touch threshold), higher order sensory functions (i.e., tactile acuity, weight and texture discrimination, haptic performance and wrist proprioception) as well as gross and fine manual dexterity were measured in both hands.
Results: The results showed that light touch threshold and tactile acuity (measured by static two point discrimination (TPD) were not significantly associated with gross or fine manual dexterity in dominant or non-dominant hand. Tactile acuity (measured by moving TPD), weight discrimination and wrist proprioception were weakly correlated with gross and fine manual dexterity in both hands. A weak to moderate significant relation was found between texture discrimination and haptic performance and both type of manual dexterity in both hands. Haptic performance predicted the largest proportion of variance in the gross manual dexterity of both hands as well as fine manual dexterity of dominant hand.
Conclusion: This study showed the low to moderate correlation between higher order sensory functions and manual dexterity in patients with idiopathic PD. Haptic performance seems to be the most influential higher order sensory function associated with manual dexterity in these patients.

Keywords

References

  1. Liu CC, Li CY, Lee PC, Sun Y. Variations in Incidence and Prevalence of Parkinson's Disease in Taiwan: A Population-Based Nationwide Study. Parkinson's disease 2016.
  2. Foki T, Pirker W, Geißler A, Haubenberger D, Hilbert M, Hoellinger I, et al. Finger dexterity deficits in Parkinson's disease and somatosensory cortical dysfunction. Parkinsonism & Related Disorders 2015;21(3):259-65.
  3. Liubicich ME, Magistro D, Candela F, Rabaglietti E, Ciairano S. Physical Activity, Fine Manual Dexterity and a Coach’s Self-Efficacy in a Physical Activity Program for Older Persons Living in Residential Care Facilities. Psychology 2012;3(05):384.
  4. Nolano M, Provitera V, Estraneo A, Selim MM, Caporaso G, Stancanelli A, et al. Sensory deficit in Parkinson's disease: evidence of a cutaneous denervation. Brain 2008;131(7):1903-11.
  5. Maschke M, Tuite PJ, Krawczewski K, Pickett K, Konczak J. Perception of heaviness in Parkinson's disease. Movement disorders 2006;21(7):1013-8.
  6. Lyoo C, Ryu Y, Lee M, Lee M. Striatal dopamine loss and discriminative sensory dysfunction in Parkinson's disease. Acta neurologica Scandinavica 2012;126(5):344-9.
  7. Kalisch T, Tegenthoff M, Dinse HR. Improvement of sensorimotor functions in old age by passive sensory stimulation. Clinical Intervention in Aging 2008;3(4):673-90.
  8. Melchior H, Vatine J-J, Weiss PL. Is there a relationship between light touch-pressure sensation and functional hand ability? Disability and rehabilitation 2007;29(7):567-75.
  9. Lee HM, Koh S-B. Many faces of Parkinson’s disease: non-motor symptoms of Parkinson’s disease. Journal of Movement Disorders 2015;8(2):92.
  10. Scalha TB, Miyasaki E, Lima NMFV, Borges G. Correlations between motor and sensory functions in upper limb chronic hemiparetics after stroke. Arquivos de Deuro-psiquiatria 2011;69(4):624-9.
  11. Wagner JM, Lang CE, Sahrmann SA, Hu Q, Bastian AJ, Edwards DF, et al. Relationships between sensorimotor impairments and reaching deficits in acute hemiparesis. Neurorehabilitation and Neural Repair 2006;20(3):406-16. 
  12. Doita M, Sakai H, Harada T, Nishida K, Miyamoto H, Kaneko T, et al. The influence of proprioceptive impairment on hand function in patients with cervical myelopathy. Spine 2006;31(14):1580-4.
  13. Casanova J, Casanova J, Young M. Hand function in patients with diabetes mellitus. Southern Medical Journal 1991;84(9):1111-3.
  14. Lee MS, Lyoo CH, Lee MJ, Sim J, Cho H, Choi YH. Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction. Movement Disorders 2010;25(15):2531-5.
  15. Domholt E. Rehabilitation research. Elsevier Saunders 2nd ED 2008.
  16. Godefroy O, Fickl A, Roussel M, Auribault C, Bugnicourt JM, Lamy C, et al. Is the Montreal Cognitive Assessment superior to the Mini-Mental State Examination to detect poststroke cognitive impairment? A study with neuropsychological evaluation. Stroke; A Journal of Cerebral Circulation 2011;42(6):1712-6.
  17. Schreuders TA, Selles RW, van Ginneken BT, Janssen WG, Stam HJ. Sensory evaluation of the hands in patients with Charcot-Marie-Tooth disease using Semmes-Weinstein monofilaments. Journal of Hand Therapy 2008;21(1):28-35.
  18. Ross RG. Rehabilitation of the Hand and Upper Extremity. Journal of Hand Therapy 2002;15(4):380.
  19. Williams PS, Basso DM, Case-Smith J, Nichols-Larsen DS. Development of the Hand Active Sensation Test: reliability and validity. Archives of physical medicine and rehabilitation 2006;87(11):1471-7.
  20. Kalisch T, Tegenthoff M, Dinse HR. Repetitive electric stimulation elicits enduring improvement of sensorimotor performance in seniors. Neural plasticity 2010.
  21. Norman JF, Crabtree CE, Norman HF, Moncrief BK, Herrmann M, Kapley N. Aging and the visual, haptic, and cross-modal perception of natural object shape. Perception 2006;35(10):1383-95.
  22. Carey LM, Oke LE, Matyas TA. Impaired limb position sense after stroke: a quantitative test for clinical use. Archives of Physical Medicine and Rehabilitation 1996;77(12):1271-8.
  23. Slota GP, Enders LR, Seo NJ. Improvement of hand function using different surfaces and identification of difficult movement post stroke in the Box and Block Test. Applied Ergonomics 2014;45(4):833-8.
  24. Desrosiers J, Bravo G, Hébert R, Dutil E, Mercier L. Validation of the Box and Block Test as a measure of dexterity of elderly people: reliability, validity, and norms studies. Archives of Physical Medicine and Rehabilitation 1994;75(7):751-5.
  25. Mehdizadeh H, Taghizadeh G, Ashayeri H. Test-retest reliability of the Purdue Pegboard test in drug on-phase for patients with Parkinson's disease. Koomesh 2010;11(3):190-8, En27.
  26. Morris S, Morris ME, Iansek R. Reliability of measurements obtained with the Timed “Up & Go” test in people with Parkinson disease. Physical therapy 2001;81(2):810-8.
  27. Fess EE. Documentation: Essential elements of an upper extremity assessment battery. Rehabilitation of the hand: Surgery and Therapy 1995; 1:185-214.
  28. Novak CB, Mackinnon SE, Kelly L. Correlation of two-point discrimination and hand function following median nerve injury. Annals of Plastic Surgery 1993;31(6):495-8.
  29. Weinstein S. Fifty years of somatosensory research: from the Semmes-Weinstein monofilaments to the Weinstein Enhanced Sensory Test. Journal of Hand Therapy 1993;6(1):11-22.
  30. Dannenbaum RM, Michaelsen SM, Desrosiers J, Levin MF. Development and validation of two new sensory tests of the hand for patients with stroke. Clinical Rehabilitation. 2002;16(6):630-9.
  31. Dellon ES, Keller KM, Moratz V, Dellon AL. Validation of cutaneous pressure threshold measurements for the evaluation of hand function. Annals of Plastic Surgery 1997;38(5):485-92.
  32. Hudspeth AJ, Jessell TM, Kandel ER, Schwartz JH, Siegelbaum SA. Principles of neural science 5nd ED; 2013.
  33. Yawalkar S. Leprosy for medical practitioners and paramedical workers.Novartis Foundation for Sustainable Development 8nd ED; 2009 
Journal of Basic and Clinical Pathophysiology
Volume 4, Issue 2
April 2016
Pages 27-36

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