Journal of Basic and Clinical Pathophysiology

Journal of Basic and Clinical Pathophysiology

Investigation of the resistance of Acinetobactor baumanii strains isolated from Tehran’s hospital inpatients in terms of selected antibiotics

Document Type : Research Paper

Authors
Mohammad Niakan 1
Rasoul Kaviani 1
Razieh Heidari Motlagh 2
Iman Pouladi 1
1 Department of Medical Microbiology, Faculty of Medicine, Shahed University of Medical Sciences, Tehran, Iran
2 School of Medicine, Shahed University, Tehran, Iran
10.22070/jbcp.2018.3463.1101
Abstract
Background and Objective: The presence of the resistant bacteria in different wards of hospitals and problems which are thereby made by these organisms in treating patients specify the necessity to identify this type of bacteria and their antibiotic resistance pattern.
Materials and Methods: In this cross-sectional study, the resistance related to 60 samples of the isolated Acintobacter baumanii was gathered from three different hospitals of Tehran and they were studied in relation to six new antibiotic groups. Antibiotic sensitivity of the selected samples were also measured based on the disk diffusion method, and then it was reviewed by the CLSI table. The studied data were finally examined using the software SPSS 16 and Reference tests.
Results: The study findings showed that piperacillin-tazobactam antibiotic has the minimum rate of sensitivity with 86.7% resistance, and with 30% resistance, a combination of ampicillin-sulbactam is of the maximum sensitivity.
Conclusion: In this study, strains isolated from the patients showed a high resistance as compared to three antibiotics, and they were placed in species resisted to some drugs. Treating such infections can be considered as a great challenge to physicians.
Keywords
Acinetobactor baumanii
Antibiotic resistance
Tigecycline
Piperacillin-tazobactam
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Journal of Basic and Clinical Pathophysiology
Volume 6, Issue 2
September 2018
Pages 13-16