The effect of task-based mirror therapy on upper limb functions and activities of daily living in patients with chronic cerebrovascular accident: A randomized control trial

Document Type: Research Paper

Authors

1 Occupational theray master of sciense student. Tehran univercity of medical sciense

2 occupational therapist, faculty of rehabilitation, Tehran university of medical sciense.

3 Associate Professor of physical therapy, faculty of Rehabilitation, Tehran University of Medical Sciences.

4 occupational therapist, faculty of rehabilitation, tehran university of medical sciense.

5 biostatist associate professor, Shahid Beheshti University.

6 physical therapist, faculty of rehabilitation, tehran university of medical sciense.

7 MSc student of occupational therapy, faculty of rehabilitation, Iran university of medical sciense.

Abstract

Background and Objective: Cerebro-Vascular Accident (CVA) is considered to be one of the main causes of acquired motor disability in adults. Different motor rehabilitation programs are being designed in order to improve motor difficulties of patients with CVA. In the current study we aimed to assess the effect of task-based mirror therapy on upper limb functions and activities of daily living in patients with CVA.
Materials and Methods: Twenty one patients with CVA were randomly divided into two groups of intervention (mirror therapy) (11 individuals) and control (10 individuals) and the both groups were receiving the usual rehabilitation protocol. The intervention group also received mirror therapy besides the usual program. Motor functions and activities of daily living were assessed via different tests (including: Box and Block test, Jebsen Taylor test, Minnesota manual dexterity test and Barthel scale) before and after the intervention course.
Results: The results showed that regarding the effect of task-based mirror therapy on different motor skills and activities of daily living, measured by mentioned tests, the main effect of time as well as the interaction effect of group × time was significant (p
Conclusion: Generally, our findings in the present investigation suggest that mirror therapy has the potential to improve upper limb function and activities of daily living in patients with chronic CVA.

Keywords


  1. Pendleton HM, Schultz-Krohn W. Pedretti's occupational therapy: practice skills for physical dysfunction: Elsevier Health Sciences; 2013.
  2. Pomeroy V, Aglioti SM, Mark VW, McFarland D, Stinear C, Wolf SL, et al. Neurological principles and rehabilitation of action disorders rehabilitation interventions. Neurorehabilitation and Neural Repair. 2011;25(5 suppl):33S-43S.
  3. Ramachandran VS, Rogers-Ramachandran D. Synaesthesia in phantom limbs induced with mirrors. Proceedings of the Royal Society of London B: Biological Sciences. 1996;263(1369):377-86.
  4. Brodie EE, Whyte A, Niven CA. Analgesia through the looking‐glass? A randomized controlled trial investigating the effect of viewing a ‘virtual’limb upon phantom limb pain, sensation and movement. European Journal of Pain. 2007;11(4):428-36.
  5. Diers M, Christmann C, Koeppe C, Ruf M, Flor H. Mirrored, imagined and executed movements differentially activate sensorimotor cortex in amputees with and without phantom limb pain. PAIN. 2010;149(2):296-304.
  6. Byl NN, McKenzie A. Treatment effectiveness for patients with a history of repetitive hand use and focal hand dystonia: a planned, prospective follow-up study. Journal of Hand Therapy. 2000;13(4):289-301.
  7. Smorenburg AR, Ledebt A, Deconinck FJ, Savelsbergh GJ. Matching accuracy in hemiparetic cerebral palsy during unimanual and bimanual movements with (mirror) visual feedback. Research in Developmental Disabilities. 2012;33(6):2088-98.
  8. De Lattre C, Descotes A, Doucet C, Faron M, Jacquemot D, Krummenacker C, et al. Prise en charge non chrirurgicale du membre superieur spastique de l enfant hemiplegique. 2015.
  9. Ramachandran VS, Seckel EL. Using mirror visual feedback and virtual reality to treat fibromyalgia. Medical Hypotheses. 2010;75(6):495-6.
  10. Ramachandran VS, Altschuler EL. The use of visual feedback, in particular mirror visual feedback, in restoring brain function. Brain. 2009:awp135.
  11. Jack D, Boian R, Merians AS, Tremaine M, Burdea GC, Adamovich SV, et al. Virtual reality-enhanced stroke rehabilitation. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 2001;9(3):308-18.
  12. Rizzo AA, Bowerly T, Buckwalter JG, Klimchuk D, Mitura R, Parsons TD. A virtual reality scenario for all seasons: the virtual classroom. Cns Spectrums. 2006;11(01):35-44.
  13. Rizzolatti G, Fabbri-Destro M, Cattaneo L. Mirror neurons and their clinical relevance. Nature Clinical Practice Neurology. 2009;5(1):24-34.
  14. Hamzei F, Läppchen CH, Glauche V, Mader I, Rijntjes M, Weiller C. Functional plasticity induced by mirror training the mirror as the element connecting both hands to one hemisphere. Neurorehabilitation and Neural Repair. 2012;26(5):484-96.
  15. Small SL, Buccino G, Solodkin A. The mirror neuron system and treatment of stroke. Developmental Psychobiology. 2012;54(3):293-310.
  16. Thieme H, Bayn M, Wurg M, Zange C, Pohl M, Behrens J. Mirror therapy for patients with severe arm paresis after stroke–a randomized controlled trial. Clinical Rehabilitation. 2013;27(4):314-24.
  17. Yavuzer G, Selles R, Sezer N, Sütbeyaz S, Bussmann JB, Köseoğlu F, et al. Mirror therapy improves hand function in subacute stroke: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2008;89(3):393-8.
  18. Iacoboni M, Mazziotta JC. Mirror neuron system: basic findings and clinical applications. Annals of Neurology. 2007;62(3):213-8.
  19. Agnew ZK, Wise RJ, Leech R. Dissociating object directed and non-object directed action in the human mirror system; implications for theories of motor simulation. PlOS ONE. 2012;7(4):e32517.
  20. Desrosiers J, Bravo G, Hébert R, Dutil E, Mercier L. Validation of the Box and Block Test as a measure of dexterity of elderly people: reliability, validity, and norms studies. Archives of Physical Medicine and Rehabilitation. 1994;75(7):751-5.
  21. Sears ED, Chung KC. Validity and responsiveness of the jebsen–taylor hand function test. The Journal of Hand Surgery. 2010;35(1):30-7.
  22. Desrosiers J, Rochette A, Hebert R, Bravo G. The minnesota manual dexterity test: Reliability, validity and reference values studies with healthy elderly people. Canadian Journal of Occupational Therapy. 1997;64(5):270-6.
  23. Tagharrobi Z, Sharifi K, Sooky Z. Psychometric evaluation of Shah version of modified Barthel index in elderly people residing in Kashan Golabchi nursing home. Journals of Kashan University of Medical Sciences. 2011;15(3).
  24. Akbarfahimi M, Karimi H, Rahimzadeh Rahbar S, Ashaeri H, Faghehzadeh S. The relationship between motor function of hemiplegic upper limb and independency in activities of daily of living in stroke patients in Tehran. Koomesh. 2011;12(3):236-43.
  25. Paik Y-R, Kim S-K, Lee J-S, Jeon B-J. Simple and task-oriented mirror therapy for upper extremity function in stroke patients: A Pilot study. Journal of Occupational Therapy. 2014;24(1):6-12.
  26. Narayan Arya K, Pandian S. Effect of task-based mirror therapy on motor recovery of the upper extremity in chronic stroke patients: A pilot study. Topics in Stroke Rehabilitation. 2013;2(30):7-210
  27. Park J-H, Heo S-Y. Systematic review on effect of mirror therapy on upper extremity function for stroke patients. The Journal of the Korea Contents Association. 2014;14(3):215-22.
  28. Wu C-Y, Huang P-C, Chen Y-T, Lin K-C, Yang H-W. Effects of mirror therapy on motor and sensory recovery in chronic stroke: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation. 2013;94(6):1023-30.
  29. Michielsen ME, Selles RW, van der Geest JN, Eckhardt M, Yavuzer G, Stam HJ, et al. Motor recovery and cortical reorganization after mirror therapy in chronic stroke patients a phase Ii randomized controlled trial. Neurorehabilitation and Neural Repair. 2011;25(3):223-33.
  30. Fogassi L, Ferrari PF, Gesierich B, Rozzi S, Chersi F, Rizzolatti G. Parietal lobe: from action organization to intention understanding. Science. 2005;308(5722):662-7.
  31. Lotze M, Halsband U. Motor imagery. Journal of Physiology-Paris. 2006;99(4):386-95.
  32. Gallese V, Fadiga L, Fogassi L, Rizzolatti G. Action recognition in the premotor cortex. Brain. 1996;119(2):593-609.
  33. Buccino G, Vogt S, Ritzl A, Fink GR, Zilles K, Freund H-J, et al. Neural circuits underlying imitation learning of hand actions: an event-related fMRI study. Neuron. 2004;42(2):323-34.
  34. Bhasin A, Srivastava MP, Kumaran SS, Bhatia R, Mohanty S. Neural interface of mirror therapy in chronic stroke patients: a functional magnetic resonance imaging study. Neurology India. 2012;60(6):570.
  35. Franceschini M, Ceravolo MG, Agosti M, Cavallini P, Bonassi S, Dall’Armi V, et al. Clinical relevance of action observation in upper-limb stroke rehabilitation a possible role in recovery of functional dexterity. A randomized clinical trial. Neurorehabilitation and Neural Repair. 2012;26(5):456-62.
  36. Prochnow D, Bermúdez i Badia S, Schmidt J, Duff A, Brunheim S, Kleiser R, et al. A functional magnetic resonance imaging study of visuomotor processing in a virtual reality‐based paradigm: Rehabilitation Gaming System. European Journal of Neuroscience. 2013;37(9):1441-7.
  37. Seitz RJ, Roland PE. Learning of sequential finger movements in man: a combined kinematic and positron emission tomography (PET) study. European Journal of Neuroscience. 1992;4(2):154-65.
  38. Grabenhorst F, Rolls ET. Value, pleasure and choice in the ventral prefrontal cortex. Trends in Cognitive Sciences. 2011;15(2):56-67.
  39. Schulte-Rüther M, Markowitsch HJ, Fink GR, Piefke M. Mirror neuron and theory of mind mechanisms involved in face-to-face interactions: a functional magnetic resonance imaging approach to empathy. Journal of Cognitive Neuroscience. 2007;19(8):1354-72.
  40. Langdon R, Corner T, McLaren J, Ward PB, Coltheart M. Externalizing and personalizing biases in persecutory delusions: the relationship with poor insight and theory-of-mind. Behaviour Research and Therapy. 2006;44(5):699-713.
  41. Hubbard IJ, Parsons MW, Neilson C, Carey LM. Task‐specific training: evidence for and translation to clinical practice. Occupational Therapy International. 2009;16(3‐4):175-89.
  42. Rizzolatti C. The mirror Neuron System and Imitation. Perspectives on Imitation: Mechanisms of imitation and imitation in animals. 2005;1:55.
  43. Buccino G, Solodkin A, Small SL. Functions of the mirror neuron system: implications for neurorehabilitation. Cognitive and Behavioral Neurology. 2006;19(1):55-63.
  44. Lyle RC. A performance test for assessment of upper limb function in physical rehabilitation treatment and research. International Journal of Rehabilitation Research. 1981;4(4):483-92.
  45. Toh SFM, Fong KN. Systematic review on the effectiveness of mirror therapy in training upper limb hemiparesis after stroke. Journal of Occupational Therapy. 2012;22(2):84-95.
  46. Radajewska A, Opara JA, Kucio C, Blaszczyszyn M, Mehlich K, Szczygiel J. The effects of mirror therapy on arm and hand function in subacute stroke in patients. International Journal of Rehabilitation Research. 2013;36(3):268-74.
  47. Lee MM, Cho H-y, Song CH. The mirror therapy program enhances upper-limb motor recovery and motor function in acute stroke patients. American Journal of Physical Medicine & Rehabilitation. 2012;91(8):689-700.
48. Lee H-W, Jeon H-S. Effects of Mirror Therapy on Motor Recovery Following a Stroke: A Meta-Analysis. Physical Therapy Korea. 2012;19(2):48-58.